Erectile dysfunction (ED) is a condition that millions of men around the globe are suffering from, and two of the well-known medications associated with erectile dysfunction are Tadalafil and Viagra, both having regular prescriptions in their treatment. Both Tadalafil (Cialis) and Viagra employ similar mechanisms to treat erectile dysfunction (ED), increasing the blood flow to the penis. However, they differ in some crucial aspects. Although the two drugs belong to similar PDE5 inhibitors, they differ in some factors.
How Tadalafil and Viagra Work
Both Tadalafil and Viagra belong to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. PDE5 is the enzyme that breaks down cyclic guanosine monophosphate (cGMP), which relaxes the muscles in the penis and allows blood to flow in, thus causing an erection. Inhibiting PDE5 increases the level of cGMP and improves erectile function in both drugs.
- Duration of Action
The main difference between Tadalafil and Viagra is that Tadalafil can be taken for up to 36 hours, while Viagra usually lasts 4-5 hours. Thus, a man can get relief from erectile dysfunction for a longer duration by taking Tadalafil, which is particularly useful for some men.
- Dosage and Administration
Both Tadalafil and Viagra are oral medications taken about 30 minutes before sexual intercourse. The introductory dose for Tadalafil is lower than that of Viagra and usually comes as ‘on-demand’ rather than daily intake.
- Side Effects
Both medications produce similar side effects, such as headache, flushing, nasal stuffiness, and dyspepsia. However, they vary in their incidence and severity.

Which Medication is Stronger?
It would be difficult to determine whether Tadalafil is more effective than Viagra as both of them work well against ED. Various working modalities have different ways and carry different durations of action. Thus, the ideal medicine will be the one that meets individual needs and preferences.
Factors to Consider
Consider several factors need to when choosing between Tadalafil and Viagra:
- Duration of action:
For a longer duration, Tadalafil may be more effective.
- Dosage and administration:
Both Tadalafil and Viagra have several dosages marketed. Sildenafil is prescribed in 25mg, 50mg, and 100mg tablets, while the various dosages for Tadalafil are 2.5mg, 5mg, 10mg, and 20mg. Health care provides a suitable dosage based on the individual’s need and tolerance.
- Side effects:
Several side effects occur with both drugs but vary by different levels of incidence or severity among individuals.
- Cost:
Cost may differ for both drugs based on insurance coverage and the purchasing place.
- Personal preferences:
The best medication will be based entirely on personal preferences.
- Talk to Your Doctor
One should consult a physician regarding taking either Tadalafil or Viagra. The doctor can advise considerations for both medications, alongside other mild risk factors or side effects.
Conclusion
Both Tadalafil and Viagra are effective medications for treating erectile dysfunction. Even though the two medications act similarly, they have some main differences, such as duration of action, dosage, and side effects. Hence, the best medicine for you depends on your needs and preferences.